英文名字 Cyclopentenone PG HPLC Mixture; Cyclopentenone Prostaglandin HPLC Mixture
中文名称 Cyclopentenone Prostaglandin HPLC Mixture (1 ea)
供应商 Cayman
产品货号 10000-1
产品报价 ¥1631.8/1 ea
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产品新闻
背景资料 This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: Prostaglandin A2, Prostaglandin B2, Prostaglandin D2, Prostaglandin E2, Prostaglandin J2, and 15-deoxy-Δ12,14-Prostaglandin J2 (100 ug each). Prostaglandin E2 and Prostaglandin D2 are both chemically unstable. In the absence of any enzymatic influence, both are undergo dehydration to form the highly UV active cyclopentenone compounds PGA2 and PGJ2, respectively. These compounds absorb in the ultraviolet with maxima at 216 - 220 lambda. The cyclopentenone prostaglandins have been noted to have antimitotic, antiviral and antitumor activity in a number of systems. PGA2 and PGJ2, can also undergo further elimination and double bond rearrangements to give PGB2 and 15-deoxy-Δ12,14 PGJ2, respectively. 15-deoxy-Δ12,14 PGJ2 is a relatively potent ligand for the PPAR.gamma. nuclear receptor. PGB2 does not appear to have significant intrinsic biological activity; however, it is frequently used as a reliable internal standard for analysis of eicosanoids by HPLC.
产品描述 This mixture contains all of the major UV-absorbing cyclopentenone prostaglandins and their precursors. Contents: Prostaglandin A2, Prostaglandin B2, Prostaglandin D2, Prostaglandin E2, Prostaglandin J2, and 15-deoxy-Δ12,14-Prostaglandin J2 (100 ug each).
产品形式 A solution in methyl acetate
产品说明书
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